940 Epithelial-microbial crosstalk modifies wound healing outcomes: from shotgun metagenomics to mechanistic understanding
نویسندگان
چکیده
منابع مشابه
Corneal epithelial wound healing.
The corneal surface is, without question, the most specialised 123 mm2* of the body's surface. It forms an integral part of the ocular surface with which it shares several anatomical and physiological attributes. Like the rest ofthe body surface, it is in a state of constant 'healing'. Squamous epithelial cells are continually shed into the tear pool and simultaneously replenished by cells movi...
متن کاملConjunctival epithelial wound healing.
In vivo conjunctival epithelial healing in albino rabbits was investigated by light microscopy following both n-heptanol and trephined conjunctival wounding. Reepithelialization occurred faster following n-heptanol treatment (3 days) versus trephination (6-7 days). No goblet cells were present in the migrating epithelium during reepithelialization. After 1 day of wounding, goblet cells disappea...
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Development of metrics for burn care, including healing of skin wounds during the acute phase of treatment, is essential in an environment of decreasing resources and increasing interest in quality and accuracy of medical information. Advantages of consensus metrics include: tracking of trends in care; consistency of care; and correlation of treatment with medical outcomes. For cutaneous burn w...
متن کاملEpithelial Regeneration and Wound Healing
SAINT in 1929 documented the experimental studies that had been carried out up to that date on the healing of oesophageal wounds. The reported observations dealt with the relatively long-term results, and little attention was paid to the early changes that occurred during the period immediately following the infliction of the wound. Recently, Malm (1951) made observations following surgical exp...
متن کاملForces driving epithelial wound healing
A fundamental feature of multicellular organisms is their ability to self-repair wounds through the movement of epithelial cells into the damaged area. This collective cellular movement is commonly attributed to a combination of cell crawling and "purse-string" contraction of a supracellular actomyosin ring. Here we show by direct experimental measurement that these two mechanisms are insuffici...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2019
ISSN: 0022-202X
DOI: 10.1016/j.jid.2019.03.1016